g protein — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T67755	Protein kinase G inhibitor-1		PKA
	Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.		PKA
T9940	Protein kinase G inhibitor-2		Others
	Protein kinase G inhibitor-2 exhibits antibacterial, antiviral, and antitumor activities.		Others
TP1902L1	G-Protein antagonist peptide acetate		Adrenergic Receptor
	G-Protein antagonist peptide acetate is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide acetate inhibits the activation of Gi or Go by M2 muscarinic cho...		Adrenergic Receptor
TP1902	G-Protein antagonist peptide
	Substance P-related peptide that inhibits binding of G proteins to their receptors. Competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.
T14898	CCG-63808		GTPase
	CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM.		GTPase
TP2254	GTP-Binding Protein Fragment, G alpha		Others
	Using specific antisera raised against synthetic peptides, we find that three distinct GTP-binding protein alpha subunits remain bound to the plasma membrane even after activation with nonhydrolyzable GTP analog. Trypsin...		Others
T14897	CCG-63802		GTPase
	CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.		GTPase
T8818	TC-G 1005		GPCR19
	TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.		GPCR19
T6512	G-418 disulfate	Geneticin,G418 Sulfate,Antibiotic G-418 sulfate,Geneticin sulfate	Antibacterial , Antibiotic
	G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation.		Antibacterial , Antibiotic
T7428	SBI-115		GPCR19
	SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5		GPCR19
T4083	BAR501	BAR 501	GPCR19
	BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).		GPCR19
TQ0252	BAR502		FXR , GPCR19 , Autophagy
	BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).		FXR , GPCR19 , Autophagy
T20731	Brilliant blue G-250	BBG,Acid blue 90, Coomassie Brilliant Blue G,Brilliant Blue G	P2X Receptor
	Brilliant blue G-250 (Acid blue 90, Coomassie Brilliant Blue G) is an antagonist of the P2X7 purinergic receptor.		P2X Receptor
T4352	SB756050	SB-756050,SB 756050	GPCR19
	SB756050 is a specific TGR5 agonist.		GPCR19
T2088	APD668	APD 668	GPR , P450 , Potassium Channel
	APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.		GPR , P450 , Potassium Channel
T5077	Deoxycholic acid sodium salt	Sodium deoxycholate,Sodium Desoxycholate	Endogenous Metabolite , GPCR19
	Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.		Endogenous Metabolite , GPCR19
TN2268	Tetrahydromagnolol		Cannabinoid Receptor , GPR , GABA Receptor
	Tetrahydromagnolol can activate cannabinoid (CB) receptors.		Cannabinoid Receptor , GPR , GABA Receptor
T2965	Deoxycholic acid	Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic	Endogenous Metabolite , GPCR19
	Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorptio...		Endogenous Metabolite , GPCR19
T6434	CCG-50014	CCG 50014	GTPase
	CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.		GTPase
T16378	Ogerin		Others , 5-HT Receptor , Adenosine Receptor
	Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak an...		Others , 5-HT Receptor , Adenosine Receptor